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免疫功能正常的患者因残留受曲霉菌污染的隐形眼镜引发结膜肿物和角膜结膜炎

Retained Aspergillus-contaminated contact lens inducing conjunctival mass and keratoconjunctivitis in an immunocompetent patient.

作者信息

Perry H D, Donnenfeld E D, Grossman G A, Stein M, Epstein A B

机构信息

Department of Ophthalmology, North Shore University Hospital, New York University College of Medicine, Manhasset, USA.

出版信息

CLAO J. 1998 Jan;24(1):57-8.

PMID:9474456
Abstract

PURPOSE

A 66-year-old woman presented with a 1-month history of prominent mucoid discharge and foreign body sensation in her left eye.

METHODS

Ocular evaluation revealed a moderately severe superficial punctate keratitis involving the temporal half of the left cornea. The superior tarsal conjunctiva showed marked papillary reaction with an area of indentation temporally. A mass was present in the superior temporal aspect of the fornix, clinically resembling a pyogenic granuloma. At the posterior aspect of this mass and covered by mucoid material, was a soft contact lens.

RESULTS

Upon removal of the lens, without any additional therapy, the patient became asymptomatic and totally resolved her keratitis and mass lesion. Cultural identification of the soft contact lens was positive for Aspergillus fumigatus.

CONCLUSIONS

We hypothesize that the mucoid discharge and mass lesion represented a mechanism similar to allergic fungal sinusitis.

摘要

目的

一名66岁女性,左眼出现1个月的大量黏液样分泌物及异物感病史。

方法

眼部检查发现左眼角膜颞侧半有中度严重的浅层点状角膜炎。上睑结膜有明显的乳头反应,颞侧有一凹陷区域。穹窿部颞上方有一肿物,临床外观类似化脓性肉芽肿。在该肿物的后方并被黏液样物质覆盖处,发现一枚软性隐形眼镜。

结果

取出隐形眼镜后,未进行任何其他治疗,患者症状消失,角膜炎及肿物病变完全消退。软性隐形眼镜的培养鉴定显示烟曲霉菌阳性。

结论

我们推测黏液样分泌物及肿物病变代表一种与变应性真菌性鼻窦炎类似的机制。

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