Mathai A, Thomas R, Braganza A, Maharajan S, George T, Muliyil J
Schell Eye Hospital, Christian Medical College, Vellore, India.
Indian J Ophthalmol. 1997 Jun;45(2):99-103.
Contrast sensitivity has been recommended as a screening and diagnostic test in primary open angle glaucoma (POAG). We tested contrast sensitivity (CS) using Vistech charts in 184 eyes of 95 patients. Three groups were examined--established primary open angle glaucoma, glaucoma suspects and age matched controls. The distribution of contrast sensitivities amongst the three groups were similar. The median contrast sensitivity of glaucoma suspects and controls were well within normal limits while that of the POAG group fell along the lower limit of normal. In all three groups the younger subjects scored better than the older, indicating a depression of contrast sensitivity with increasing age. Even if depression of any one spatial frequency was considered abnormal, the test yielded a sensitivity of 55.4% and specificity of 69.5%. Similarly contrast sensitivity testing was found to be of little use in detecting field defects a maximum sensitivity of 47.3% and specificity of 73.3%. Vistech contrast sensitivity testing is not a useful test in POAG screening or diagnosis.
对比敏感度已被推荐作为原发性开角型青光眼(POAG)的一种筛查和诊断测试。我们使用Vistech图表对95例患者的184只眼睛进行了对比敏感度(CS)测试。研究了三组对象——确诊的原发性开角型青光眼患者、青光眼疑似患者和年龄匹配的对照组。三组之间对比敏感度的分布相似。青光眼疑似患者和对照组的对比敏感度中位数均在正常范围内,而原发性开角型青光眼组的对比敏感度中位数则处于正常下限。在所有三组中,年轻受试者的得分均高于年长受试者,这表明对比敏感度会随着年龄增长而降低。即使将任何一个空间频率的降低视为异常,该测试的敏感度为55.4%,特异度为69.5%。同样,对比敏感度测试在检测视野缺损方面作用不大,其最大敏感度为47.3%,特异度为73.3%。Vistech对比敏感度测试在原发性开角型青光眼的筛查或诊断中并非有用的测试。