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国家发布的指南对急诊部门对扑热息痛中毒管理的影响。国家中毒信息服务中心。

The impact of nationally distributed guidelines on the management of paracetamol poisoning in accident and emergency departments. National Poison Information Service.

作者信息

Bialas M C, Evans R J, Hutchings A D, Alldridge G, Routledge P A

机构信息

Welsh National Poisons Unit, Llandough Hospital, Cardiff, UK.

出版信息

J Accid Emerg Med. 1998 Jan;15(1):13-7. doi: 10.1136/emj.15.1.13.

DOI:10.1136/emj.15.1.13
PMID:9475215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1343000/
Abstract

OBJECTIVE

To assess the impact of the treatment guidelines on the management of paracetamol self poisoning in accident and emergency (A&E) departments.

METHODS

24 A&E departments in Wales and England provided details of their management of paracetamol poisoning before and after the distribution of national treatment guidelines to all A&E departments in the United Kingdom.

RESULTS

Significant increases were seen in the availability of formal written policies, the display of treatment nomograms, the recommendation to treat beyond 16 hours after ingestion, and to use a lower line on the treatment nomogram for patients at special risk of paracetamol induced liver damage.

CONCLUSIONS

Regularly updated guidelines in the management of paracetamol poisoning should be displayed in A&E departments so that medical and nursing personnel have access to the best current information on the treatment of poisoning with this frequently used drug.

摘要

目的

评估治疗指南对急症室扑热息痛自服中毒处理的影响。

方法

威尔士和英格兰的24个急症室提供了在向英国所有急症室分发国家治疗指南前后其扑热息痛中毒处理的详细情况。

结果

在正式书面政策的可得性、治疗图谱的展示、摄入后16小时以上治疗的建议以及对扑热息痛诱发肝损伤特殊风险患者使用治疗图谱上较低界限方面均有显著增加。

结论

急症室应展示定期更新的扑热息痛中毒处理指南,以便医护人员能够获取关于这种常用药物中毒治疗的最新最佳信息。

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本文引用的文献

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Severe hepatotoxicity, acute renal failure, and pancytopenia in a young child after repeated acetaminophen overdosing.
Clin Pediatr (Phila). 1994 Jan;33(1):42-5. doi: 10.1177/000992289403300107.
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Paracetamol toxicity: is enzyme induction important?
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