Faruque A S, Hoque S S, Fuchs G J, Mahalanabis D
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka.
Acta Paediatr. 1997 Dec;86(12):1308-11. doi: 10.1111/j.1651-2227.1997.tb14903.x.
A randomized clinical trial was carried out to compare a packaged ready-to-mix rice oral rehydration solution (ORS) to the standard glucose ORS for the treatment of childhood diarrhoea. Children were of either gender, aged 3-35 months, presenting with a history of watery diarrhoea for 72 h or less. The main outcomes examined were stool output, ORS intake, duration of diarrhoea and nutritional recovery during follow-up at 16 d of illness. Stool output in the first 24 h (106 vs 107 g kg(-1)), ORS intake in clinic (93 vs 102 ml per motion) and duration of diarrhoea (88 h vs 81 h) were similar in the two treatment groups. The few episodes that became persistent were similar (2%) in the two groups. The weight gain during follow-up was similar in the two ORS groups.
开展了一项随机临床试验，以比较预混包装大米口服补液盐（ORS）与标准葡萄糖ORS治疗儿童腹泻的效果。研究对象为3至35个月的儿童，无论性别，出现水样腹泻病史72小时及以内。主要观察指标包括粪便排出量、ORS摄入量、腹泻持续时间以及发病16天时随访期间的营养恢复情况。两个治疗组在前24小时的粪便排出量（106 vs 107 g·kg⁻¹）、门诊ORS摄入量（每次排便93 vs 102 ml）和腹泻持续时间（88小时 vs 81小时）相似。两组中转为持续性腹泻的病例数相近（均为2%）。两个ORS组在随访期间的体重增加情况相似。
