Askenazi J, Carlson C J, Alpert J S, Dexter L
Circulation. 1976 Sep;54(3):480-3. doi: 10.1161/01.cir.54.3.480.
Eight patients with mixed mitral stenosis and regurgitation underwent hemodynamic and angiographic study prior to mitral valve replacement. The stenotic orifice of the mitral valve was calculated employing the total left ventricular stroke volume by cineangiography as the numerator of the Gorlin Formula. Excellent agreement with the measured orifice of the mitral valve was obtained using a value of 37.9 (0.85 X 44.5) for the constant in the Gorlin formula as recommended by Cohen and Gorlin. Recalculation of this constant independently by our data yielded a value that was almost identical. Regurgitant flows and orifice sizes were calculated for each patient using the same constant as for calculation of the stenotic orifices.
八名患有二尖瓣狭窄并反流的患者在进行二尖瓣置换术前接受了血流动力学和血管造影研究。二尖瓣狭窄口采用电影血管造影术测得的左心室总搏出量作为戈林公式的分子来计算。按照科恩和戈林的建议，在戈林公式中使用37.9（0.85×44.5）作为常数，与二尖瓣测量口取得了极佳的一致性。根据我们的数据独立重新计算该常数，得出的值几乎相同。使用与计算狭窄口相同的常数，为每位患者计算反流流量和瓣口大小。
