Prenatal diagnosis of trisomy 18 at the 10-14-week ultrasound scan.
作者信息
Sherod C, Sebire N J, Soares W, Snijders R J, Nicolaides K H
机构信息
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
出版信息
Ultrasound Obstet Gynecol. 1997 Dec;10(6):387-90. doi: 10.1046/j.1469-0705.1997.10060387.x.
Abstract
A beneficial consequence of screening for trisomy 21 by a combination of maternal age and fetal nuchal translucency thickness (NT) at 10-14 weeks is the early diagnosis of trisomy 18. In a multicenter study of 91,091 singleton pregnancies there were 106 fetuses with trisomy 18 and 83% were identified by NT screening. Trisomy 18 was also associated with early onset intrauterine growth retardation, decreased fetal heart rate and the presence of exomphalos.
摘要
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