Reinis Z, Pokorný J, Bazika V, Horáková D, Tiserová J, Reisenauer R
Cor Vasa. 1976;18(2):129-38.
A longitudinal epidemiological study of ischaemic heart disease (IHD) in men aged 40-59 years showed that the five-year incidence of the manifest form was 7.8% in agricultural workers and 9.7% in industrial employees. The corresponding incidence of the latent form was 9.0% and 12.2%, respectively. The differences in the incidence of both forms between the population samples studied was at the border of statistical significance. The importance of risk factors was evaluated on the basis of the score represented by the difference between the respective five-year incidence of IHD in subjects with and without the risk factors concerned. The highest relative scores were found with systolic and diastolic hypertension, positive family history and obesity. For prognostic purposes, the total relative risk, represented by the sum of the scores of the risk factors proved to be useful. Autopsies confirmed that a total relative risk exceeding 40% was a sensitive indicator of morphological substrate of coronary heart disease.
一项针对40至59岁男性缺血性心脏病（IHD）的纵向流行病学研究表明，明显症状形式的五年发病率在农业工人中为7.8%，在产业雇员中为9.7%。潜伏形式的相应发病率分别为9.0%和12.2%。所研究的人群样本中两种形式发病率的差异处于统计学意义的临界值。基于有和没有相关风险因素的受试者中IHD各自五年发病率之差所代表的评分来评估风险因素的重要性。收缩压和舒张压高血压、阳性家族史和肥胖的相对评分最高。为了预后目的，由风险因素评分总和表示的总相对风险被证明是有用的。尸检证实，总相对风险超过40%是冠心病形态学基础的一个敏感指标。
