Sharma V, Persad E, Kueneman K
Department of Psychiatry, University of Western Ontario, London Psychiatric Hospital, Canada.
J Affect Disord. 1998 Jan;47(1-3):123-9. doi: 10.1016/s0165-0327(97)00131-6.
We examined the risk factors for suicide among inpatients in an Ontario provincial psychiatric hospital.
Forty-four inpatients who had committed suicide during their hospital stay from 1969 to 1995 were compared with a group of inpatient controls matched for sex, age and date of admission. The diagnosis for each patient was reviewed by the authors.
Suicide victims were more likely to have had a mood disorder, family history of psychiatric problems, mention of suicide risk in chart notes and a previous suicide attempt. Two findings necessitated further scrutiny: The most common diagnosis among inpatients who committed suicide in this study was a mood disorder and not schizophrenia as previously reported. A large proportion of patients (24) had experienced a rapidly fluctuating clinical course prior to the time of suicide.
The implications of these findings, including the possible role of antidepressants in the induction of cycling prior to suicide, are discussed.
我们研究了安大略省一家省级精神病医院住院患者的自杀风险因素。
将1969年至1995年住院期间自杀的44名患者与一组在性别、年龄和入院日期相匹配的住院对照患者进行比较。作者对每位患者的诊断进行了复查。
自杀患者更有可能患有情绪障碍、有精神疾病家族史、病历记录中提及自杀风险以及有过自杀未遂史。有两项发现需要进一步审查:本研究中自杀的住院患者最常见的诊断是情绪障碍,而非先前报道的精神分裂症。很大一部分患者(24名)在自杀前经历了快速波动的临床病程。
讨论了这些发现的意义,包括抗抑郁药在自杀前诱发病情循环中可能发挥的作用。