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法国和瑞典两家汽车公司男性员工心血管风险状况比较。心脏项目组。

Comparison of cardiovascular risk profile between male employees of two automotives companies in France and Sweden. The Coeur Project Group.

作者信息

Simon A, Dimberg L, Levenson J, Lanoiselée C, Massonneau M, Eriksson B, Jern S, Kumlin L, Marin P, Dahlöf B, Hansson L, Björntorp P

机构信息

Broussais Hospital, Paris, France.

出版信息

Eur J Epidemiol. 1997 Dec;13(8):885-91. doi: 10.1023/a:1007428624757.

Abstract

To determine whether or not the lower rate of coronary disease in France, in comparison with Sweden, might be explained by different cardiovascular risk profiles, a cross-sectional analysis (first step of a longitudinal study) of comparable samples of automotive workers was carried out in corporate occupational health clinics of Renault and Volvo. Traditional cardiovascular risk factors were evaluated and the Framingham coronary risk was estimated for 1000 randomly selected 45-50 years old Caucasian males from each company. Compared with the Frenchmen, the Swedish men consisted of more white collar workers and were slightly older. After adjustment for age and blue/white collar status, the Swedish men showed lower body mass indexes, waist to hip rations and heart rates, lower frequency of treatment of hypercholesterolemia and diabetes than the Frenchmen. The Swedish males also exhibited higher averages of blood cholesterol, low density lipoprotein (LDL) cholesterol and glucose, but lower frequencies of hypercholestrolemia and diabetes, and a higher frequency of family histories of cardiovascular disease. Blood pressure, hypertension prevalence, triglycerides level, and high density lipoprotein (HDL) did not differ between the groups. The average number of traditional risk factors was 1.1/person for the Frenchmen and 0.8/person for the Swedes. However, the coronary risk as estimated using the Framingham index was not different between the groups. This, together with the more frequent family history of cardiovascular disease in Swedish men, suggests a lower susceptibility to risk factors as a possible explanation for the lower cardiovascular disease prevalence reported in France, and/or the possibility that factors not measured were involved.

摘要

为了确定与瑞典相比,法国冠心病发病率较低是否可能由不同的心血管风险状况所解释,在雷诺和沃尔沃公司的职业健康诊所对汽车工人的可比样本进行了横断面分析(纵向研究的第一步)。评估了传统心血管危险因素,并对每家公司随机抽取的1000名45 - 50岁白种男性估计了弗雷明汉冠心病风险。与法国男性相比,瑞典男性中白领工人更多且年龄稍大。在对年龄和蓝领/白领身份进行调整后,瑞典男性的体重指数、腰臀比和心率较低,高胆固醇血症和糖尿病的治疗频率低于法国男性。瑞典男性的血胆固醇、低密度脂蛋白(LDL)胆固醇和血糖平均值也较高,但高胆固醇血症和糖尿病的发生率较低,心血管疾病家族史的发生率较高。两组之间的血压、高血压患病率、甘油三酯水平和高密度脂蛋白(HDL)没有差异。法国男性传统危险因素的平均数量为每人1.1个,瑞典男性为每人0.8个。然而,使用弗雷明汉指数估计的冠心病风险在两组之间没有差异。这一点,再加上瑞典男性中更常见的心血管疾病家族史,表明对危险因素的易感性较低可能是法国报告的心血管疾病患病率较低的一个解释,和/或未测量的因素可能起作用的可能性。

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