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[变应性鼻结膜炎患者对食物的皮肤反应性]

[Cutaneous reactivity to foods among patients with allergic rhinoconjunctivitis].

作者信息

Ortega Cisneros M, Vidales Díaz M A, del Río Navarro B E, Sienra Monge J J

机构信息

Departamento de Neumología y Alergia, Hospital Infantil de México Federico Gómez, México, DF.

出版信息

Rev Alerg Mex. 1997 Nov-Dec;44(6):153-7.

PMID:9477665
Abstract

Ocular allergy could be induced by food allergy or inhaled allergens. However there are few pediatric studies about it. Our objective was to know the frequency in children who have food allergy as cause of their ocular allergy. We perform a prospective and descriptive study in 50 patients within 6 to 16 years of age during June 1996 to January 1997. Skin prick tests to food allergens and inhalants, serum IgE levels by ELISA (enzyme immunoassay), nasal and conjunctival cytology were done. Not paired student T-test, Mann-Whitney U, and Kruskall-Wallis test were used for statistical analysis. We found mean of age 9.1 years +/- 2.5. Prick tests were positives to foods in 20%, 50% to inhalants and 30% to both. Food allergens seen more frequently were shellfish, tomato, rice, peanut and inhaled allergen Dermatophagoides pteronissinus. Serum IgE was elevated and ocular cytology was positive in food hypersensitivity group with significance difference (p = 0.023). In conclusion, we found a high frequency (50%) of food hypersensitivity in patients with allergic rhinoconjunctivitis.

摘要

眼部过敏可能由食物过敏或吸入性过敏原引起。然而,关于这方面的儿科研究很少。我们的目的是了解因食物过敏导致眼部过敏的儿童的发生率。我们在1996年6月至1997年1月期间对50名6至16岁的患者进行了一项前瞻性描述性研究。进行了针对食物过敏原和吸入性过敏原的皮肤点刺试验、通过酶联免疫吸附测定(ELISA)检测血清IgE水平、鼻和结膜细胞学检查。采用非配对学生t检验、曼-惠特尼U检验和克鲁斯卡尔-沃利斯检验进行统计分析。我们发现平均年龄为9.1岁±2.5岁。皮肤点刺试验显示,对食物过敏的占20%,对吸入性过敏原过敏的占50%,对两者都过敏的占30%。更常见的食物过敏原是贝类、番茄、大米、花生,吸入性过敏原是屋尘螨。食物过敏超敏反应组的血清IgE升高且眼部细胞学检查呈阳性,差异有统计学意义(p = 0.023)。总之,我们发现变应性鼻结膜炎患者中食物过敏超敏反应的发生率很高(50%)。

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