Caires G, Aguiar C, Parreira L, Adragão P, Morgado F, Bonhorst D, Grilo M J, Mesquita F, Seabra-Gomes R
Serviço de Cardiologia, Hospital de Santa Cruz, Carnaxide, Portugal.
Rev Port Cardiol. 1997 Nov;16(11):863-71, 847-8.
To determine the value of the Cardiac Event Recorder (CER) in the diagnosis and treatment orientation of bradydysrhythmias, tachydysrhythmias and ischaemic events, based on our experience at the Santa Cruz Hospital.
We retrospectively analysed 100 consecutive patients tested with a CER between January 1990 and December 1996 (mean follow-up, 272 +/- 202 days); the mean age of the patients (66 women and 34 men) was 45 +/- 18 years (range: 7 to 83); structural cardiac disease was present in 34% of the patients. CER was indicated for the investigation of symptoms suggestive of bradydysrhythmias (pre-syncope and/or syncope)--Group B--in 24 patients, tachydysrhythmias (palpitations and/or tachycardia sensation)--Group T--in 72 patients and ischaemic events--Group I--in the remaining four patients. We compared these groups with respect to demographic characteristics, prevalence of structural cardiac disease and efficacy of the test in the investigation of symptoms; periodicity of symptoms and duration of CER testing were analysed. In patients that experienced typical symptoms during the test, we analysed the electrocardiogram recorded at the time of the event and we investigated whether abnormal ECG findings influenced the therapeutic approach and whether this led to better symptomatic outcome.
Patients in groups B and T were mainly women (54 percent vs 74 percent, NS). Group B patients were older than group T patients (mean age, 56.4 +/- 17.8 vs 40.0 +/- 16.0 yrs, P < 0.001). In group B, structural cardiac disease was less prevalent (37.5% vs 78.0%, P < 0.001) and symptom periodicity was greater (weekly: 12.5% vs 78.0%, monthly: 87.5% vs 15.2%, P < 0.001) than in group T. Duration of CER testing and number of events recorded were similar in the two groups. In both, CER testing was an important aid for therapeutic approach. Twenty two patients (eight B, 13 T and one I) had no typical symptomatic episodes during the CER test; in the remaining 78 patients (16 B, 59 T and three I), an electrocardiogram recording during such episodes was available for analysis. The ECG was abnormal in 44 of these patients, 12 (75%) being of group B and 32 (54%) of group T. Symptom periodicity was a few weeks in 65% of all patients (6 B, 57 T and two I). Duration of CER testing was < or = two weeks in 91 percent of the patients (22 B, 65 T and four I). CER testing guided the therapeutic approach in 78% of all patients. Changes of treatment strategy were more frequent in patients with CER documented typical symptomatic episodes than in those without (46% vs 9%, P < 0.02). When changes of treatment occurred, symptomatic outcome was better (97% vs 55%, P < 0.001).
The CER is an important guide for the diagnostic and therapeutic approach for patients with intermittent arrhythmia suggesting, symptoms (78% of patients). A recording of normal ECG during typical symptoms reassures the patient and excludes potentially toxic treatments. Our selection of patients for CER testing seemed adequate since most typical symptomatic events occurred during the first two weeks of the test; longer duration of CER testing seems unnecessary.
基于我们在圣克鲁斯医院的经验,确定心脏事件记录仪(CER)在缓慢性心律失常、快速性心律失常及缺血性事件的诊断和治疗导向中的价值。
我们回顾性分析了1990年1月至1996年12月期间连续接受CER检测的100例患者(平均随访时间为272±202天);患者平均年龄为45±18岁(范围:7至83岁),其中女性66例,男性34例;34%的患者存在结构性心脏病。24例患者(B组)因怀疑有缓慢性心律失常(先兆晕厥和/或晕厥)症状而接受CER检测,72例患者(T组)因怀疑有快速性心律失常(心悸和/或心动过速感)症状而接受检测,其余4例患者(I组)因怀疑有缺血性事件而接受检测。我们比较了这些组在人口统计学特征、结构性心脏病患病率以及症状调查中检测的有效性方面的差异;分析了症状的周期性和CER检测的持续时间。对于在检测期间出现典型症状的患者,我们分析了事件发生时记录的心电图,并调查异常心电图结果是否影响治疗方法以及这是否导致更好的症状转归。
B组和T组患者主要为女性(分别为54%和74%,无显著差异)。B组患者比T组患者年龄大(平均年龄分别为56.4±17.8岁和40.0±16.0岁,P<0.001)。与T组相比,B组中结构性心脏病的患病率较低(分别为37.5%和78.0%,P<0.001),症状周期性更高(每周发作:分别为12.5%和78.0%,每月发作:分别为87.5%和15.2%,P<0.001)。两组的CER检测持续时间和记录的事件数量相似。在两组中,CER检测对治疗方法均有重要帮助。22例患者(8例B组、13例T组和1例I组)在CER检测期间未出现典型症状发作;其余78例患者(16例B组、59例T组和3例I组)在发作期间有心电图记录可供分析。其中44例患者的心电图异常,B组12例(75%),T组32例(54%)。65%的患者症状周期性为几周(6例B组、57例T组和2例I组)。91%的患者CER检测持续时间≤两周(22例B组、65例T组和4例I组)。CER检测指导了78%患者的治疗方法。有CER记录的典型症状发作的患者比没有的患者治疗策略改变更频繁(分别为46%和9%,P<0.02)。当发生治疗改变时,症状转归更好(分别为97%和55%,P<0.001)。
对于有间歇性心律失常提示症状的患者(78%的患者),CER是诊断和治疗方法的重要指导。典型症状期间心电图记录正常可使患者安心并排除潜在的毒性治疗。我们对CER检测患者的选择似乎是合适的,因为大多数典型症状事件发生在检测的前两周;似乎没有必要进行更长时间的CER检测。