Zirvi K A, Jehangir S, Jarboe C H
Farmaco Sci. 1976 Jul;31(7):546-8.
A group of nine diamides of cyclobutane-1,1-dicarboxylic acid has been prepared and examined for general depressant and analgesic activity. Several showed activity in both respects but with little overlap. Several compounds were evaluated for anticonvulsant and myorelaxant activity. No activity was found.
已制备了一组9种环丁烷-1,1-二羧酸二酰胺,并对其进行了一般的镇静和镇痛活性检测。有几种在这两方面均显示出活性,但重叠较少。对几种化合物进行了抗惊厥和肌松活性评估,未发现活性。