Kamenczak A, Jasińska-Kolawa K, Targosz D, Szkolnicka B, Sancewicz-Pach K
Department of Clinical Toxicology, Collegium Medicum, Jagiellonian University, Kraków.
Przegl Lek. 1997;54(10):671-6.
The aim of the study was to evaluate the number and the course of acute pesticides poisoning treated in the Department of Clinical Toxicology in 1986-1995. During that period 264 cases (189 men and 75 women) of acute pesticides poisoning were treated. Suicidal oral ingestion followed by inhalation and dermal exposure was the most common cause of acute intoxication. Organophosphates and carbamates were the most common cause of acute intoxication. Poisonings with dipyridyls and sulfonylurea derivatives are relatively rare. The highest number of poisonings was noted in age group 30-39 years. In 37% of the total analysed cases the co-ingestion of ethanol was noted. As organophosphorous compounds were the most common cause of acute pesticides poisoning, the gastric lavage + intensive care treatment + specific and non-specific antidotes were the most common therapeutic management. Duration of hospitalisation was dependent on the kind of pesticide. The longest hospitalisation required the patients poisoned with organophosphates. A full recovery was noted in 57.6% of poisoned patients. 34.1% of patients suffered different organ injury mostly from respiratory and central nervous system. 22 (8.3%) the fatal cases were noted in analysed period.
该研究的目的是评估1986 - 1995年临床毒理学部门治疗的急性农药中毒病例数量及病程。在此期间,共治疗了264例急性农药中毒病例(189名男性和75名女性)。急性中毒最常见的原因是口服自杀,其次是吸入和皮肤接触。有机磷和氨基甲酸酯是急性中毒最常见的原因。联吡啶和磺酰脲衍生物中毒相对较少见。中毒人数最多的年龄组为30 - 39岁。在所有分析病例中,37%的患者同时摄入了乙醇。由于有机磷化合物是急性农药中毒最常见的原因,洗胃 + 重症监护治疗 + 特异性和非特异性解毒剂是最常见的治疗方法。住院时间取决于农药种类。有机磷中毒患者住院时间最长。57.6%的中毒患者完全康复。34.1%的患者出现不同程度的器官损伤,主要是呼吸系统和中枢神经系统。在分析期间,共记录到22例(8.3%)死亡病例。