Yen S S, Rebar R W, Quesenberry W
J Clin Endocrinol Metab. 1976 Jul;43(1):132-6. doi: 10.1210/jcem-43-1-132.
Neuroendocrine assessments were made in a 16-year-old girl with pseudocyesis of 38 weeks duration. Basal levels of pituitary LH and PRL, but not of FSH, were markedly elevated and the pulsatile pattern of LH and PRL appears to be exaggerated compared with those found in normal cycling women. Growth hormone levels were normal, with an appropriate increase after arginine infusion and l-dopa. The increased luteotropic action resulting from increased plasma LH and the lactogenic action of increased plasma PRL were associated with the presence of luteal function and galactorrhea. The dominant role of psychic mechanism(s) in causing hypersecretions of LH and PRL is suggested by the almost immediate fall in the serum concentrations and the rapid resolution of abdominal distention after the diagnosis was revealed to the patient.
对一名患有持续38周假孕的16岁女孩进行了神经内分泌评估。垂体促黄体生成素(LH)和催乳素(PRL)的基础水平显著升高,但促卵泡生成素(FSH)的基础水平未升高,与正常月经周期的女性相比,LH和PRL的脉冲模式似乎更为明显。生长激素水平正常,精氨酸输注和左旋多巴后有适当升高。血浆LH升高导致的促黄体作用增强以及血浆PRL升高的泌乳作用与黄体功能和溢乳的存在有关。向患者揭示诊断后,血清浓度几乎立即下降且腹胀迅速消退,这表明心理机制在导致LH和PRL分泌过多中起主导作用。