Budka H, Guseo A, Jellinger K, Mittermayer K
J Neurol Sci. 1976 Aug;28(4):459-68. doi: 10.1016/0022-510x(76)90117-9.
Light- and electron-microscope studies were performed on CSF cells from a patient with CNS leukaemia presenting with an intermittent meningitic reaction. Numerous fully matured basophilic and eosinophilic granulocytes with excess glycogen content accompained undifferentiated leukaemic blast cells in the CSF. Such a CSF cell reaction has not been previously reported. It is suggested that this isolated CSF reaction represents a special type of immediate hypersensitivity reaction triggered by an abnormal leukaemic giant cell clone, and mitigated by the accompanying eosinophilic granulocytes.
对一名患有中枢神经系统白血病并伴有间歇性脑膜炎反应的患者的脑脊液细胞进行了光镜和电镜研究。脑脊液中大量糖原含量过高的完全成熟嗜碱性粒细胞和嗜酸性粒细胞与未分化的白血病原始细胞同时存在。这种脑脊液细胞反应此前未见报道。有人认为，这种孤立的脑脊液反应代表了一种由异常白血病巨细胞克隆引发、并由伴随的嗜酸性粒细胞减轻的特殊类型的速发型超敏反应。
