[用于红细胞浓缩的白细胞滤器的比较]

[Comparison of leukocyte filters for erythrocyte concentration].

作者信息

Hiller J, Lubitz B, Dominka T, Kühnl P

机构信息

Universitäts-Krankenhaus Eppendorf, Hamburg, Deutschland.

出版信息

Beitr Infusionsther Transfusionsmed. 1994;32:20-2.

PMID:9480086

Abstract

UNLABELLED

We compared the following leukocyte filter blood systems (BBS): Biotrans Bio R01 Plus, Diamed Sepacell RS-200, Pall BPF4 (log 4 filters) and Biotrans Bio R01 (log 3 filter). We evaluated the leukocyte removal, handling, the increase of free hemoglobin and the loss of red blood cells (RBC) by filtration. A total of 54 buffy-coat-reduced RBCs were suspended in 200 ml PAGGS-M, stored at +4 degrees C for 24 h and filtered subsequently. Samples were taken before storage, immediately before and after filtration to measure total and free Hb and the white blood cell (WBC) contamination.

RESULTS

(1) All log 4 filters showed a comparable reduction of the WBC content per RBC concentrate. (2) Differences were observed in total filtration time and loss of RBCs: Biotrans Bio R01 Plus and Pall BPF4 yielded significantly better results than Diamed Sepacell RS-200. (3) The log 3 filter did not meet the criteria of < 5 x 10(6) WBCs per filtered unit of RBCs (as recommended by the Council of Europe).

摘要

未标记

我们比较了以下白细胞过滤血液系统（BBS）：Biotrans Bio R01 Plus、Diamed Sepacell RS - 200、颇尔BPF4（对数4过滤器）和Biotrans Bio R01（对数3过滤器）。我们评估了白细胞去除情况、操作过程、游离血红蛋白的增加以及过滤导致的红细胞（RBC）损失。总共54份去除白细胞层的红细胞悬浮于200 ml PAGGS - M中，在+4℃储存24小时，随后进行过滤。在储存前、过滤前及过滤后立即取样，以测量总血红蛋白和游离血红蛋白以及白细胞（WBC）污染情况。

结果

（1）所有对数4过滤器对每份红细胞浓缩物中白细胞含量的降低效果相当。（2）在总过滤时间和红细胞损失方面存在差异：Biotrans Bio R01 Plus和颇尔BPF4的结果明显优于Diamed Sepacell RS - 200。（3）对数3过滤器未达到每过滤单位红细胞<5×10⁶个白细胞的标准（欧洲委员会推荐标准）。