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[胰腺癌姑息治疗的回顾性研究]

[Retrospective study on palliative treatment of pancreatic cancer].

作者信息

Zemełka T, Rysz B

机构信息

Kliniki Chemioterapii, Instytuto Onkologii w Krakowie.

出版信息

Przegl Lek. 1997;54(7-8):547-50.

PMID:9480467
Abstract

A retrospective analysis included 119 patients with inoperable pancreatic cancer confirmed in histological examination. This group of patients was treated in Memorial Cancer Institute Cracow Branch between 1950 and 1993. The study revealed that a palliative operation (gastroduodenostomy, cholangioenterostomy or cholangiogastrostomy) was the factor of great influence on the time of survival. The average survival in operated versus not operated patients was 7.5 months and 4.0 months, respectively. Another factor exerting influence on the survival appeared to be the progression of the neoplastic process. The average survival in case of locally advanced versus disseminated disease was 6.9 and 2.3 months, respectively. Although the survival in the group of patients who underwent chemotherapy was longer, the significance of this method of treatment can not be estimated as the group was not numerous enough. The time from the beginning of symptoms and from the first physical examination to establishing diagnosis has prolonged in the last decade.

摘要

一项回顾性分析纳入了119例经组织学检查确诊为无法手术切除的胰腺癌患者。这组患者于1950年至1993年期间在克拉科夫纪念癌症研究所分院接受治疗。研究表明,姑息性手术(胃十二指肠吻合术、胆管肠吻合术或胆管胃吻合术)是对生存时间有重大影响的因素。接受手术与未接受手术的患者平均生存期分别为7.5个月和4.0个月。另一个对生存有影响的因素似乎是肿瘤进程的进展。局部晚期与播散性疾病患者的平均生存期分别为6.9个月和2.3个月。尽管接受化疗的患者组生存期更长,但由于该组患者数量不足,无法评估这种治疗方法的意义。在过去十年中,从出现症状开始以及从首次体格检查到确诊的时间有所延长。

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