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印度全民食盐加碘的相关性与重要性。

Relevance and importance of universal salt iodization in India.

作者信息

Sood A, Pandav C S, Anand K, Sankar R, Karmarkar M G

机构信息

Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Natl Med J India. 1997 Nov-Dec;10(6):290-3.

PMID:9481104
Abstract

It is well known that iodine and thyroid hormone are essential for normal development of the human brain and body. Lack of iodine in the diet leads to 'visible' and 'invisible' spectrum of iodine deficiency disorders. The prevalence of iodine deficiency can be assessed by estimating the total goitre rate in the population. A large section of the Indian population suffers from iodine deficiency disorders. These are easily preventable as was shown more than 40 years ago in the study conducted in Kangra Valley. Salt is the best medium of iodine supplementation in India. The potential risks of iodine supplementation, including the risk of iodine-induced thyrotoxicosis, are discussed. Finally, we attempt to formulate policy guidelines on iodine supplementation on the basis of presumed risk:benefit ratio for carrying out an iodine supplementation programme. Taking into consideration medical, social, economic and political aspects of universal salt iodization, the benefits far outweigh the potential low risk due to iodine excess in a small segment of the population.

摘要

众所周知,碘和甲状腺激素对人类大脑和身体的正常发育至关重要。饮食中缺碘会导致一系列“可见”和“不可见”的碘缺乏症。碘缺乏的患病率可通过估算人群中的甲状腺肿总患病率来评估。很大一部分印度人口患有碘缺乏症。正如40多年前在康格拉山谷进行的研究所表明的那样,这些疾病很容易预防。在印度,盐是补充碘的最佳媒介。文中讨论了碘补充的潜在风险,包括碘诱发甲状腺毒症的风险。最后,我们试图根据实施碘补充计划假定的风险效益比来制定碘补充的政策指南。考虑到全民食盐加碘的医学、社会、经济和政治方面,其益处远远超过一小部分人群因碘过量而产生的潜在低风险。

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