Masip J, Vecilla F, Páez J
Int J Cardiol. 1998 Jan 5;63(1):95-7. doi: 10.1016/s0167-5273(97)00285-4.
We report a patient with diffuse pulmonary hemorrhage after streptokinase therapy for acute myocardial infarction. Hemoptysis, anemia, fever, jaundice, progressive bilateral pulmonary infiltrates and severe acute respiratory failure were observed. The patient required mechanical ventilation and recovered successfully. An immunological reaction to a highly antigenic agent such as streptokinase is considered in the pathogenesis of this complication.
我们报告了1例在接受链激酶治疗急性心肌梗死后发生弥漫性肺出血的患者。观察到咯血、贫血、发热、黄疸、进行性双侧肺部浸润及严重的急性呼吸衰竭。该患者需要机械通气并成功康复。这种并发症的发病机制考虑为对链激酶这类高抗原性药物的免疫反应。
