Brewin C R, Watson M, McCarthy S, Hyman P, Dayson D
Department of Psychology, Royal Holloway, University of London.
Psychol Med. 1998 Jan;28(1):219-24. doi: 10.1017/s0033291797006028.
Intrusive memories of stressful events, many involving illness and death, are found in a minority of depressed cancer patients, and may predict the course of anxiety and depression.
Matched samples of mild to moderately depressed and non-depressed cancer patients were followed up after 6 months. Anxiety and depression at follow-up were related to measures of intrusive memories of stressful life events and autobiographical memory functioning that had been assessed at baseline.
Levels of anxiety and depression remained fairly constant over time in the two groups, and the depressed group continued to experience high levels of intrusive memories. The presence of intrusive memories at baseline, and the extent to which these memories were consciously avoided, predicted greater anxiety at follow-up, even after controlling for initial severity of physical and psychiatric symptoms. None of the measures of memory functioning predicted levels of depression at follow-up.
Intrusive memories appear to be a marker of more prolonged psychopathology in cancer patients and may respond to direct therapeutic intervention.
在少数患癌抑郁症患者中发现了对压力事件（其中许多涉及疾病和死亡）的侵入性记忆，这些记忆可能预示焦虑和抑郁的病程。
对轻度至中度抑郁的癌症患者和非抑郁癌症患者的匹配样本进行了6个月的随访。随访时的焦虑和抑郁与基线时评估的压力生活事件侵入性记忆及自传体记忆功能的测量指标相关。
两组患者的焦虑和抑郁水平随时间保持相当稳定，抑郁组继续经历高水平的侵入性记忆。即使在控制了身体和精神症状的初始严重程度之后，基线时存在侵入性记忆以及有意识避免这些记忆的程度，仍预示着随访时更高的焦虑水平。记忆功能的各项测量指标均未预测随访时的抑郁水平。
侵入性记忆似乎是癌症患者更持久精神病理学的一个标志，可能对直接的治疗干预有反应。
