Starovoĭtova M N, Guseva N G
Ter Arkh. 1997;69(11):55-60.
60 cases of scleroderma systematica with onset in the childhood or adolescence have been analyzed. Juvenile scleroderma took, as a rule, a favourable course (78%). Slow progression was observed in 43% of patients. Stabilization occurred in 20% of cases. A complete regression was seen in 15%. The disease ran unfavorably in 5% of the cases. Overlap-syndrome occupied an intermediate position between favourable and unfavourable disease. It was registered in 17% of cases. The prognosis is better in early detection of the symptoms and choice of adequate therapy.
对60例儿童期或青春期起病的系统性硬皮病患者进行了分析。青少年硬皮病通常病程良好(78%)。43%的患者病情进展缓慢。20%的病例病情稳定。15%的病例完全缓解。5%的病例病情进展不利。重叠综合征在病情良好和不利之间处于中间位置,17%的病例出现该情况。早期发现症状并选择适当治疗,预后较好。