Mohammad A R, Bauer R L, Yeh C K
Department of Dental Medicine and Public Health, University of Southern California School of Dentistry, Los Angeles, USA.
Int J Prosthodont. 1997 Jul-Aug;10(4):381-5.
Osteoporosis has been suggested to contribute to the edentulous condition. However, studies specifically designed to examine the relationship between tooth loss and osteoporosis are scarce, and reported results have been mixed. This study investigated the correlation between tooth loss and spinal bone density in a nonHispanic white female population. Forty-four subjects were recruited and divided into high and low spinal bone density groups based on whether the bone density was higher or lower than the age-adjusted population mean bone density. Missing teeth and periodontal status in these groups were assessed and analyzed. Tooth loss was not significantly different between subjects with low spinal bone density (4.90 +/- 0.89 teeth) and high spinal bone density (3.81 +/- 0.90 teeth). Tooth loss did not differ after age and periodontal adjustment. However, the loss of attachment levels (relative to the cementoenamel junction) was greater in the low spinal bone density subjects (3.42 +/- 0.30 mm) than in the high spinal bone density subjects (2.37 +/- 0.26 mm) (P < .05). The difference may have resulted from gingival recession (P < .05), because the gingival pocket depths were not significantly different between the two groups. In this study, total tooth loss was not directly associated with systemic bone density. However, periodontal disease was negatively associated with spinal bone density. Whether periodontal disease will ultimately lead to greater tooth loss in low spinal bone density group merits further investigation.
骨质疏松症被认为与无牙状况有关。然而，专门设计用于研究牙齿脱落与骨质疏松症之间关系的研究很少，且报告的结果也不一致。本研究调查了非西班牙裔白人女性人群中牙齿脱落与脊柱骨密度之间的相关性。招募了44名受试者，并根据骨密度高于或低于年龄校正后的人群平均骨密度，将其分为高脊柱骨密度组和低脊柱骨密度组。对这些组中的缺失牙和牙周状况进行了评估和分析。低脊柱骨密度受试者（4.90±0.89颗牙）和高脊柱骨密度受试者（3.81±0.90颗牙）之间的牙齿脱落情况无显著差异。在进行年龄和牙周调整后，牙齿脱落情况也没有差异。然而，低脊柱骨密度受试者（3.42±0.30毫米）相对于牙骨质釉质界的附着水平丧失比高脊柱骨密度受试者（2.37±0.26毫米）更大（P<.05）。这种差异可能是由于牙龈退缩导致的（P<.05），因为两组之间的牙龈袋深度没有显著差异。在本研究中，牙齿总脱落与全身骨密度没有直接关联。然而，牙周疾病与脊柱骨密度呈负相关。牙周疾病是否最终会导致低脊柱骨密度组中更多的牙齿脱落，值得进一步研究。
