Janssen B J, Williams A, Chen J J, Mathern J, Hake S, Sinha N
Section of Plant Biology, University of California, Davis 95616, USA.
Plant Mol Biol. 1998 Feb;36(3):417-25. doi: 10.1023/a:1005925508579.
Homeobox genes are known to play a role in developmental regulation. The knotted-like homeobox (knox) genes fall into two classes. The class I knox genes like knl, stml, and knatl are involved in maintaining meristem identity in cells. The function of class II knox genes is at yet undetermined. We have characterized two knox genes from tomato. LeT6 and LeT12 map to distinct chromosome locations that are different from the location for a recently cloned knox gene from tomato, tknl, confirming that plant homeobox genes are not clustered on chromosomes. These genes have a distinct expression pattern. Unlike other class I knl-like genes, LeT6 is expressed in developing lateral organs and developing ovaries in flowers. LeT12 is more ubiquitously expressed in the mature plant. RNA in situ localization data suggest that both these genes may have a role to play in formative events in ovule and embryo morphogenesis.
已知同源异型盒基因在发育调控中发挥作用。类结瘤同源异型盒（knox）基因分为两类。I类knox基因如knl、stml和knatl参与维持细胞中的分生组织特性。II类knox基因的功能尚未确定。我们对来自番茄的两个knox基因进行了表征。LeT6和LeT12定位于不同的染色体位置，这与最近从番茄中克隆的一个knox基因tknl的位置不同，证实了植物同源异型盒基因在染色体上并非成簇分布。这些基因具有独特的表达模式。与其他I类knl样基因不同，LeT6在发育中的侧器官和花中发育的子房里表达。LeT12在成熟植株中表达更为广泛。RNA原位定位数据表明，这两个基因可能在胚珠和胚胎形态发生的形成过程中发挥作用。
