Cheng W, Saing H
Department of Surgery, University of Hong Kong, Duchess of Kent Children's Hospital, Sandy Bay, Hong Kong.
J Paediatr Child Health. 1997 Dec;33(6):515-6. doi: 10.1111/j.1440-1754.1997.tb01661.x.
Bleeding and wound infection are the most common complications of circumcision. Cyanoacrylate tissue glue has been claimed to have the advantage of being haemostatic, bacteriostatic and easy to use. The purpose of this study is to assess the feasibility of using the tissue glue in approximation of circumcision wound in children.
A prospective randomized trial was carried out on 86 boys consecutively admitted into the Duchess of Kent Children's Hospital, Hong Kong. The results of wound approximation with cyanoacrylate tissue glue and suturing with interrupted 4/0 plain catgut were compared. The operations were carried out by the same surgeon using identical technique except for the wound approximation. The wound was assessed 1 day, 2 days, 3 days, 1 week and 1 month postoperatively.
There was no statistically significant difference between the two groups in the rates of wound inflammation, infection, bleeding, dehiscence and cosmetic appearance, but the duration of operation was longer using tissue glue (19.8 min vs 16.5 min, P = 0.002).
We conclude that tissue glue approximation of circumcision wounds in children is a feasible alternative, but it offers no extra advantage when compared to suturing.
出血和伤口感染是包皮环切术最常见的并发症。有人声称氰基丙烯酸酯组织胶水具有止血、抑菌且使用方便的优点。本研究的目的是评估在儿童包皮环切伤口闭合中使用该组织胶水的可行性。
对连续入住香港玛丽医院的86名男孩进行了一项前瞻性随机试验。比较了使用氰基丙烯酸酯组织胶水闭合伤口和用4/0普通肠线间断缝合的结果。除伤口闭合方式外，手术由同一位外科医生采用相同技术进行。术后1天、2天、3天、1周和1个月对伤口进行评估。
两组在伤口炎症、感染、出血、裂开和外观方面的发生率无统计学显著差异，但使用组织胶水时手术时间更长（19.8分钟对16.5分钟，P = 0.002）。
我们得出结论，在儿童包皮环切伤口中使用组织胶水闭合是一种可行的替代方法，但与缝合相比没有额外优势。
