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TP53 intron 6 polymorphism and the risk of ovarian and breast cancer.

作者信息

Mavridou D, Gornall R, Campbell I G, Eccles D M

出版信息

Br J Cancer. 1998 Feb;77(4):676-7. doi: 10.1038/bjc.1998.108.

DOI:10.1038/bjc.1998.108
PMID:9484829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2149940/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8b7/2149940/0a1ae419d2fb/brjcancer00080-0166-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8b7/2149940/0a1ae419d2fb/brjcancer00080-0166-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8b7/2149940/0a1ae419d2fb/brjcancer00080-0166-a.jpg

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1
TP53 intron 6 polymorphism and the risk of ovarian and breast cancer.TP53基因内含子6多态性与卵巢癌和乳腺癌风险
Br J Cancer. 1998 Feb;77(4):676-7. doi: 10.1038/bjc.1998.108.
2
The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas.TP53基因第72位密码子多态性可能影响乳腺癌中TP53突变的功能，但对结直肠癌并无影响。
Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1684-8.
3
p53 polymorphism in ovarian and breast cancer.卵巢癌和乳腺癌中的p53基因多态性
Lancet. 1996 Feb 10;347(8998):393-4. doi: 10.1016/s0140-6736(96)90569-3.
4
Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations.在17p13.3上，位于TP53远端的一个基因作为无p53突变的乳腺肿瘤中等位基因缺失靶点的证据。
Cancer Res. 1994 Aug 1;54(15):4200-6.
5
An intronic deletion in TP53 gene causes exon 6 skipping in breast cancer.TP53基因的内含子缺失导致乳腺癌中6号外显子跳跃。
Eur J Cancer. 1997 Aug;33(9):1479-83. doi: 10.1016/s0959-8049(97)00136-6.
6
p53 polymorphism in ovarian and bladder cancer.卵巢癌和膀胱癌中的p53基因多态性
Lancet. 1995 Jul 15;346(8968):182. doi: 10.1016/s0140-6736(95)91239-8.
7
An intronic variant in the TP53 gene in Serbian women with cervical or ovarian cancer.塞尔维亚宫颈癌或卵巢癌女性中TP53基因的一个内含子变异体。
Cancer Genet Cytogenet. 2010 Apr 15;198(2):173-5. doi: 10.1016/j.cancergencyto.2010.01.006.
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Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer.TP53和p21WAF1/Cip1基因常见多态性与乳腺癌表型特征之间的关联。
Carcinogenesis. 2002 Feb;23(2):311-5. doi: 10.1093/carcin/23.2.311.
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HaeIII polymorphism in intron 1 of the human p53 gene.
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An intronic variant in the TP53 gene in a Brazilian woman with breast cancer.一名患有乳腺癌的巴西女性的TP53基因内含子变异。
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Impact on breast cancer susceptibility and clinicopathological traits of common genetic polymorphisms in and genes in Sardinian women.撒丁岛女性中BRCA1和BRCA2基因常见基因多态性对乳腺癌易感性及临床病理特征的影响。
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TP53 Gene Polymorphisms and Occupational Skin Cancer Risks for Workers of Glass Fiber Manufacture.TP53基因多态性与玻璃纤维制造工人的职业性皮肤癌风险
Iran J Public Health. 2017 Nov;46(11):1495-1501.
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本文引用的文献

1
A novel germ line p53 mutation in intron 6 in diverse childhood malignancies.多种儿童恶性肿瘤中第6内含子的一种新的种系p53突变。
Oncogene. 1997 Apr 3;14(13):1541-5. doi: 10.1038/sj.onc.1200990.
2
p53 polymorphism in ovarian and breast cancer.卵巢癌和乳腺癌中的p53基因多态性
Lancet. 1996 Feb 10;347(8998):393-4. doi: 10.1016/s0140-6736(96)90569-3.
3
A novel polymorphism in intron 6 of the human p53 gene: a possible association with cancer predisposition and susceptibility.
乳腺癌中 Arg72Pro TP53 和-710 C/T VEGFR1 多态性的上位性相互作用：易感性和生存。
Mol Cell Biochem. 2013 Jul;379(1-2):181-90. doi: 10.1007/s11010-013-1640-8. Epub 2013 Apr 6.
4
Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment.p53及p53信号通路中的多态性：在癌症易感性及治疗反应中的作用
J Cell Mol Med. 2009 Mar;13(3):440-53. doi: 10.1111/j.1582-4934.2008.00634.x.
5
Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.TP53区域的单核苷酸多态性与侵袭性上皮性卵巢癌易感性
Cancer Res. 2009 Mar 15;69(6):2349-57. doi: 10.1158/0008-5472.CAN-08-2902. Epub 2009 Mar 10.
6
Mutation and homozygous deletion analyses of genes that control the G1/S transition of the cell cycle in skin melanoma: p53, p21, p16 and p15.皮肤黑色素瘤中控制细胞周期G1/S转换的基因的突变和纯合缺失分析：p53、p21、p16和p15
Clin Transl Oncol. 2005 May;7(4):156-64. doi: 10.1007/BF02708753.
7
Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B.黑色素瘤中控制G1/S细胞周期的基因的突变分析：TP53、CDKN1A、CDKN2A和CDKN2B。
BMC Cancer. 2005 Apr 8;5:36. doi: 10.1186/1471-2407-5-36.
8
Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility.除BRCA1和BRCA2之外的与乳腺癌易感性相关的基因。
J Med Genet. 2002 Apr;39(4):225-42. doi: 10.1136/jmg.39.4.225.
9
Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations.p53基因的内含子变异与卵巢癌风险增加相关，但在BRCA1或BRCA2种系突变携带者中并非如此。
Br J Cancer. 1999 Sep;81(1):179-83. doi: 10.1038/sj.bjc.6690669.
DNA Cell Biol. 1995 Dec;14(12):983-90. doi: 10.1089/dna.1995.14.983.
4
p53-based blood test for p53PIN3 and risk for sporadic ovarian cancer.基于p53的血液检测用于检测p53PIN3及散发性卵巢癌风险。
Lancet. 1995 Apr 15;345(8955):994. doi: 10.1016/s0140-6736(95)90745-9.
5
p53 polymorphism in ovarian and bladder cancer.卵巢癌和膀胱癌中的p53基因多态性
Lancet. 1995 Jul 15;346(8968):182. doi: 10.1016/s0140-6736(95)91239-8.