Levanon D, Zhang M, Orr W C, Chen J D
Thomas N. Lynn Institute for Healthcare Research, Oklahoma City, Oklahoma 73112, USA.
Am J Physiol. 1998 Feb;274(2):G430-4. doi: 10.1152/ajpgi.1998.274.2.G430.
The absence of a standard meal in electrogastrography may limit its clinical significance. Different meals may fail to produce the expected postprandial motility pattern. The aim of this study was to investigate the effect of meal volume and composition on postprandial myoelectrical activity. Fourteen healthy subjects were given four meals that differed from a "reference meal" in one single parameter (volume, calorie, or fiber content). Gastric myoelectrical activity was measured using surface electrogastrography. Spectral and statistical analyses were performed to investigate the effect of food properties on electrogastrogram (EGG) parameters. It was found that the reference meal produced a postprandial increase in the dominant frequency (P < 0.007), dominant power (P < 0.04), and percentage of normal 2-4 cycle/min gastric slow waves (P > 0.05). Similar changes were observed with the low-volume and high-fiber meals but not with the reduced-calorie meal. Fasting EGG parameters in all four sessions showed no significant difference. It was concluded that low-calorie meals do not result in expected postprandial physiological responses and thus are not appropriate for EGG tests. A volume reduction of down to one-half the volume of a regular meal does not affect postprandial changes of the EGG; thus a condensed test meal may be recommended for symptomatic patients.
在胃电图检查中缺乏标准餐食可能会限制其临床意义。不同的餐食可能无法产生预期的餐后运动模式。本研究的目的是调查餐食体积和成分对餐后肌电活动的影响。14名健康受试者被给予四餐，这些餐食在单一参数（体积、热量或纤维含量）上与“参考餐”不同。使用表面胃电图测量胃肌电活动。进行频谱和统计分析以研究食物特性对胃电图（EGG）参数的影响。结果发现，参考餐食使餐后主导频率增加（P < 0.007）、主导功率增加（P < 0.04），正常2 - 4次/分钟胃慢波的百分比增加（P > 0.05）。低体积和高纤维餐食也观察到类似变化，但低热量餐食未观察到。所有四个时段的空腹EGG参数均无显著差异。得出的结论是，低热量餐食不会导致预期的餐后生理反应，因此不适用于EGG测试。餐食体积减少至正常餐食体积的一半不会影响EGG的餐后变化；因此，对于有症状的患者，可推荐浓缩测试餐。
