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[局限性牛痘/猫痘病毒感染。流行病学、诊断与治疗方面]

[Localized cowpox/cat pox virus infection. Aspects of epidemiology, diagnosis and therapy].

作者信息

Conrad A, Czerny C P, Kapp A, Kiehl P

机构信息

Dermatologische Klinik und Poliklinik der Medizinischen Hochschule Hannover.

出版信息

Hautarzt. 1997 Dec;48(12):918-22. doi: 10.1007/s001050050686.

DOI:10.1007/s001050050686
PMID:9486365
Abstract

Only few human cowpox/catpox infections have been reported until now. The diagnosis of bland localized infections may be missed, if this disease is not well known. However, early diagnosis of localized cowpox/catpox infections is important, since at least immunocompromised patients are at risk of potential lethal generalization similar to generalized variola vera. Using a typical case report, the characteristics of the disease, as well as the current aspects of epidemiology, diagnosis and therapy are summarized. The characteristic finding of intracytoplasmatic inclusion bodies by light microscopy can be demonstrated in a human biopsy-specimen for the first time and greatly facilitated the diagnosis.

摘要

迄今为止,仅有少数人类牛痘/猫痘感染的病例被报道。如果对这种疾病了解不足,可能会漏诊无症状的局部感染。然而,局部牛痘/猫痘感染的早期诊断很重要,因为至少免疫功能低下的患者有发生类似重症天花致死性播散的风险。通过一个典型病例报告,总结了该疾病的特征以及当前流行病学、诊断和治疗方面的情况。首次在人类活检标本中通过光学显微镜观察到胞质内包涵体这一特征性表现,极大地促进了诊断。

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