远端厚皮性多指（趾）畸形

Distal pachydermodactyly.

作者信息

Tompkins S D, McNutt N S, Shea C R

机构信息

Division of Dermatology, University of California, San Diego, USA.

出版信息

J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):359-62. doi: 10.1016/s0190-9622(98)70584-5.

DOI:10.1016/s0190-9622(98)70584-5

PMID:9486717

Abstract

An 80-year-old white woman had a 6-year history of enlarging, intradermal plaques on the distal, volar, and lateral surfaces of the fingers. A biopsy specimen showed whorled, densely aggregated bundles of coarsely thickened collagen within a sparsely cellular papillary and reticular dermis. The fibrosis entrapped eccrine sweat coils and focally extended into the subcutis. This case represents an unusual, predominantly acral form of acquired, progressive, cutaneous fibrosis, which we propose to call distal pachydermodactyly.

摘要

一名80岁白人女性，手指远端、掌侧及外侧的皮内斑块逐渐增大已有6年病史。活检标本显示，在细胞稀少的乳头层和网状真皮内，有呈漩涡状、密集聚集的粗大增厚胶原束。纤维化包绕了小汗腺螺旋管，并局部延伸至皮下组织。该病例代表了一种罕见的、以肢端为主的获得性、进行性皮肤纤维化形式，我们提议将其称为远端厚皮性指端炎。