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[间质立体定向近距离放射治疗的三维导航]

[3D navigation for interstitial stereotaxic brachytherapy].

作者信息

Auer T, Hensler E, Eichberger P, Bluhm A, Gunkel A, Freysinger W, Bale R, Gaber O, Thumfart W F, Lukas P

机构信息

Klinik für Strahlentherapie und Radioonkologie, Universität Innsbruck.

出版信息

Strahlenther Onkol. 1998 Feb;174(2):82-7. doi: 10.1007/BF03038480.

Abstract

AIM

The aim of this paper is to describe the adaption of 3D-navigation for interstitial brachytherapy. The new method leads to prospective and therefore improved planning of the therapy (position of the needle and dose distribution) and to the possibility of a virtual simulation (control if vessels or nerves are on the pathway of the needle).

MATERIAL AND METHODS

The EasyGuide Neuro navigation system (Philips) was adapted in the way, that needles for interstitial brachytherapy were made connectable to the pointer and correctly displayed on the screen. To determine the positioning accuracy, several attempts were performed to hit defined targets on phantoms. Two methods were used: "free navigation", where the needle was under control of the navigation system, and the "guided navigation" where an aligned template was used additionally to lead the needle to the target. In addition a mask system was tested, whether it met the requirements of stable and reproducible positioning. The potential of applying this method in clinical practice was tested with an anatomical specimen.

RESULTS

About 91% of all attempts lied within 5 mm. There were even better results on the more rigid table (94% < 4 mm). No difference could be seen between both application methods ("free navigation" and "navigation with template"), they showed the same accuracy.

CONCLUSIONS

The accuracy of the phantom experiments and the confirmation by the experiment with the anatomical specimen showed that excellent results can be expected in clinical practice using rigid tables and patient supporting systems.

摘要

目的

本文旨在描述三维导航在组织间近距离放射治疗中的应用。这种新方法可实现前瞻性的、因而得到改进的治疗计划(针的位置和剂量分布),并可进行虚拟模拟(检查血管或神经是否位于针的路径上)。

材料与方法

对EasyGuide神经导航系统(飞利浦公司)进行了改装,使组织间近距离放射治疗用的针能够与指示器相连并在屏幕上正确显示。为确定定位精度,在体模上进行了多次尝试以命中确定的目标。使用了两种方法:“自由导航”,即针由导航系统控制;“引导导航”,即额外使用一个对齐模板将针引导至目标。此外,还测试了一种面罩系统,看其是否符合稳定且可重复定位的要求。用一个解剖标本测试了该方法在临床实践中的应用潜力。

结果

所有尝试中约91%的落点在5毫米范围内。在更坚硬的平台上结果更好(94% < 4毫米)。两种应用方法(“自由导航”和“使用模板导航”)之间未发现差异,它们显示出相同的精度。

结论

体模实验的精度以及解剖标本实验的验证表明,在临床实践中使用坚硬平台和患者支撑系统有望获得优异的结果。

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