Schaanning J
Scand J Respir Dis. 1976;57(2):63-72.
Thirty-four patients with chronic obstructive lung disease were exercised stepwise up to maximal work load. V02 at maximal work load showed a slightly significant correlation to FEV1, while a closer association with VC as well as Ve and Vt was noted. In most patients Vt during maximal exercise was around 50% of VC, while no such limit was present when Vt was related to FEV1. These patterns were independent of the clinical type of obstructive lung disease. At 300 kpm/min (50 W) Vt/VC% as well as heart rate was negatively correlated to V02 max, but not to FEV1. No significant relationship was seen between V02 or Ve at this exercise level and V02 max, as well as FEV1. The ventilatory pattern during exercise seemed to reflect the patients' ventilatory strain more adequately than pre-exercise FEV1. The negative relationship between heart rate during moderate exercise and V02 max might further reflect this strain.
34例慢性阻塞性肺疾病患者逐步进行运动直至达到最大工作量。最大工作量时的V02与FEV1呈轻度显著相关，同时发现与VC以及Ve和Vt的关联更为密切。大多数患者在最大运动时的Vt约为VC的50%，而当Vt与FEV1相关时则不存在这样的限制。这些模式与阻塞性肺疾病的临床类型无关。在300 kpm/min（50 W）时，Vt/VC%以及心率与V02 max呈负相关，但与FEV1无关。在此运动水平下，V02或Ve与V02 max以及FEV1之间未发现显著关系。运动期间的通气模式似乎比运动前的FEV1更能充分反映患者的通气负荷。中度运动时心率与V02 max之间的负相关可能进一步反映了这种负荷。
