Schaanning J
Scand J Respir Dis. 1978;59(6):313-8.
Respiratory cycle time components during rest and graded exercise were measured in 18 patients with chronic obstructive lung disease, and compared with controls matched for sex and age. For a given exercise level (50 W) increased minute ventilation was present in the patients. This was due to shorter cycle time. Both inspiratory and expiratory time shortened to the same degree rendering the ratio inspiratory time/total respiratory cycle time similar in the two groups. At maximal exercise total respiratory cycle time and inspiratory time was shorter in the patients than in the control group, but the ratio between them was still similar. However, for a given total cycle time during maximal exercise inspiratory time was shorter. Inspiratory time and the ratio inspiratory time/total cycle time as measured during 50 W exercise, were positively correlated with the patient's exercise capacity, but not of sufficient accuracy for useful prediction of the latter. The difference in concomitant variation of tidal volume and inspiratory time during exercise ventilation between the patients and the control subjects seemed satisfactorily explained by the different lung volumes at which the two groups were breathing.
对18例慢性阻塞性肺疾病患者在静息和分级运动期间的呼吸周期时间成分进行了测量，并与年龄和性别相匹配的对照组进行了比较。在给定的运动水平（50瓦）下，患者的分钟通气量增加。这是由于周期时间缩短。吸气时间和呼气时间均缩短至相同程度，使得两组的吸气时间/总呼吸周期时间比值相似。在最大运动时，患者的总呼吸周期时间和吸气时间比对照组短，但两者之间的比值仍然相似。然而，在最大运动期间，对于给定的总周期时间，吸气时间较短。在50瓦运动期间测量的吸气时间和吸气时间/总周期时间比值与患者的运动能力呈正相关，但预测后者的准确性不足。患者和对照受试者在运动通气期间潮气量和吸气时间伴随变化的差异似乎可以通过两组呼吸时不同的肺容量得到满意的解释。
