Wenzel M, Schönhofer B, Siemon K, Köhler D
Krankenhaus Kloster Grafschaft, Zentrum für Pneumologie, Beatmungs- und Schlafmedizin, Schmallenberg-Grafschaft.
Pneumologie. 1997 Dec;51(12):1108-10.
Recently a nose plaster (NP, Breathe-Right) has been increasingly used in the treatment of obstructive sleep apnoea (OSA) and snoring. Hence, we examined the use of the NP as a treatment of both OSA and snoring without OSA. The NP has a elastic spine that increases the diameter of the nostril and is thought to reduce the degree of OSA and snoring. According to the polysomnographic data two groups were differentiated: Group A (30 patients with OSA, apnoea index > 10/h, 26 men) and Group B (20 snorers, without OSA, 13 men). After the diagnostic polysomnography the efficacy of the NP was measured with a cardiorespiratory polygraph on the 2 following nights. In the group A the polygraphic data (apnoea index, time of apneas, desaturation index, time of desaturations, mean and nadir SaO2) were studied; in group B the snoring index (snoring events/hour) was measured. A questionnaire scored quality of sleeping, daytime condition and the quality of nose breathing. In neither group were the recorded polygraphic findings different with the NP although with the NP an improved nose breathing was scored in both groups. In group A 90% of the patients scored the daytime sleepiness unchanged and 10 of 30 patients described an improved quality of sleep. In group B there was no change in the frequency of snoring events with the NP. Neither the degree of OSA nor of snoring without OSA were changed by the NP, which can therefore not be considered a treatment of these conditions. However, the majority of the study population were impressed by the symptomatic improvement in nose breathing.
最近，一种鼻贴（NP，畅呼吸）越来越多地用于治疗阻塞性睡眠呼吸暂停（OSA）和打鼾。因此，我们研究了鼻贴作为治疗OSA和无OSA的打鼾的方法。鼻贴有一个弹性脊柱，可增加鼻孔直径，被认为可以降低OSA和打鼾的程度。根据多导睡眠图数据分为两组：A组（30例OSA患者，呼吸暂停指数>10/h，26名男性）和B组（20名打鼾者，无OSA，13名男性）。在诊断性多导睡眠图检查后，在接下来的两个晚上用心肺多导记录仪测量鼻贴的疗效。在A组中研究了多导睡眠图数据（呼吸暂停指数、呼吸暂停时间、去饱和指数、去饱和时间、平均和最低血氧饱和度）；在B组中测量了打鼾指数（每小时打鼾事件数）。通过问卷调查对睡眠质量、白天状况和鼻呼吸质量进行评分。两组使用鼻贴时记录的多导睡眠图结果均无差异，尽管两组使用鼻贴时鼻呼吸评分均有所改善。在A组中，90%的患者白天嗜睡评分不变，30名患者中有10名表示睡眠质量有所改善。在B组中，使用鼻贴时打鼾事件的频率没有变化。鼻贴既没有改变OSA的程度，也没有改变无OSA的打鼾程度，因此不能认为它是治疗这些疾病的方法。然而，大多数研究对象对鼻呼吸的症状改善印象深刻。
