原发性尿道上裂患儿尿失禁的内镜治疗

Endoscopic treatment of urinary incontinence in children with primary epispadias.

作者信息

Duffy P G, Ransley P G

机构信息

Great Ormond Street Hospital for Children NHS Trust, Institute of Urology, Middlesex Hospital, London, UK.

出版信息

Br J Urol. 1998 Feb;81(2):309-11. doi: 10.1046/j.1464-410x.1998.00538.x.

DOI:10.1046/j.1464-410x.1998.00538.x

PMID:9488077

Abstract

OBJECTIVE

To evaluate the efficacy of the endoscopic insertion of polydimethylsiloxane particles (Macroplastique, Uroplasty Inc) (MPQ) into the posterior urethral region of boys with urinary incontinence and primary epispadias.

PATIENTS AND METHODS

Between 1991 and 1995, 12 boys aged 3-7 years (mean 4.8) received an endoscopic submucosal injection with MPQ into the posterior urethra to correct urinary incontinence; the 12 boys were wet day and night. All patients had undergone a modified Cantwell epispadias repair before injection. The procedure was performed 24 times with a total volume of 83 mL of material injected into 59 sites in the posterior urethra (mean volume per injection 1.4 mL). The mean follow-up after injection was 10.8 months (range 3-22).

RESULTS

Three patients became completely dry, the degree of incontinence was improved in six and there was no change in three.

CONCLUSION

The preliminary results of this relatively non-invasive treatment are encouraging.

摘要

目的

评估经内镜将聚二甲基硅氧烷颗粒（Macroplastique，Uroplasty公司）（MPQ）注入患有尿失禁和原发性尿道上裂男孩的后尿道区域的疗效。

患者与方法

1991年至1995年间，12名年龄在3至7岁（平均4.8岁）的男孩接受了经内镜将MPQ黏膜下注射到后尿道以纠正尿失禁的治疗；这12名男孩日夜均有尿失禁。所有患者在注射前均接受了改良的坎特韦尔尿道上裂修复术。该操作共进行了24次，总共83毫升材料被注入后尿道的59个部位（每次注射平均体积为1.4毫升）。注射后的平均随访时间为10.8个月（范围3至22个月）。