Kushner B J
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA.
Arch Ophthalmol. 1998 Feb;116(2):189-94. doi: 10.1001/archopht.116.2.189.
Patients with intermittent exotropia may have an increase in their angle of strabismus in the distance when the angle is measured either after 1 hour of monocular occlusion or while the patients fixate on a distant target outdoors. The hypothesis that surgery should be performed for this larger deviation has been suggested but not tested.
To test the hypothesis that surgery should be performed for the increased angle of strabismus in the distance in patients with intermittent exotropia and to investigate the factors that influence the angle of misalignment.
A prospective, clinical trial was conducted of patients with intermittent exotropia in whom the angle of misalignment in the distance increased after 1 hour of monocular occlusion or while the patients fixated on an outdoor target. The study group underwent surgery for the largest deviation measured; the control group underwent surgery for the initial angle measured at 6 m. All patients in whom the angle of misalignment increased while the patients were looking at an outdoor target were additionally measured in indoor illumination at 24 m and also at 6 m under floodlights that simulated outdoor illumination. Ninety patients undergoing surgery were randomized.
Forty-three (86.0%) of the 50 patients undergoing surgery for the largest angle measured had a satisfactory outcome vs 25 (62.5%) of the 40 patients in the control group (P<.001). The mechanism for the increase in exotropia while fixating on an outdoor target was studied in 76 patients, and the results were variable.
The angle of strabismus in patients with intermittent exotropia undergoing surgery should be measured while the patients fixate on an outdoor target and after 1 hour of monocular occlusion. Surgery should be performed for the largest angle measured.
间歇性外斜视患者在单眼遮盖1小时后或在户外注视远处目标时测量斜视角度,其远距离斜视角度可能会增加。有人提出应对这种较大的偏差进行手术,但尚未得到验证。
验证间歇性外斜视患者远距离斜视角度增加时应进行手术的假设,并研究影响斜视角度的因素。
对间歇性外斜视患者进行前瞻性临床试验,这些患者在单眼遮盖1小时后或注视户外目标时远距离斜视角度增加。研究组针对测量到的最大偏差进行手术;对照组针对在6米处测量的初始角度进行手术。所有在注视户外目标时斜视角度增加的患者,还在24米的室内照明下以及在模拟户外照明的泛光灯下6米处进行测量。90例接受手术的患者被随机分组。
针对测量到的最大角度进行手术的50例患者中,43例(86.0%)效果满意,而对照组40例患者中有25例(62.5%)效果满意(P<0.001)。对76例患者研究了注视户外目标时外斜视增加的机制,结果各不相同。
间歇性外斜视患者手术时,应在患者注视户外目标时以及单眼遮盖1小时后测量斜视角度。应针对测量到的最大角度进行手术。