Candelario Nellowe, Lo Kevin Bryan, Naranjo Mario
Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
BMJ Case Rep. 2017 Mar 17;2017:bcr2016218630. doi: 10.1136/bcr-2016-218630.
Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition characterised by calcification and ossification of the vertebral ligaments. It is most commonly seen to affect the thoracic and lumbar vertebrae and is usually seen among elderly men. The cause of this condition is unknown. Risk factors include male gender, obesity, diabetes and advancing age. The majority of these cases are found incidentally on imaging and patients are generally asymptomatic. Cervical DISH is less common than its thoracic and lumbar counterparts. When symptomatic, it can cause dysphagia or sometimes airway compromise. If this happens, surgical intervention should be performed. Although a rare cause of dysphagia, DISH is easily diagnosed with imaging. When identified, surgical decompression produces very good clinical outcomes.
弥漫性特发性骨肥厚(DISH)是一种非炎性疾病,其特征为椎体韧带钙化和骨化。该病最常累及胸椎和腰椎,多见于老年男性。病因不明。危险因素包括男性、肥胖、糖尿病和年龄增长。这些病例大多在影像学检查时偶然发现,患者通常无症状。颈椎DISH比胸椎和腰椎DISH少见。有症状时,可导致吞咽困难,有时还会影响气道。若出现这种情况,应进行手术干预。尽管DISH是吞咽困难的罕见病因,但通过影像学检查很容易诊断。一经确诊,手术减压可产生非常好的临床效果。