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[髋关节置换术后大面积肺栓塞的早期阿韦利辛治疗]

[Early Awelysin therapy in massive pulmonary embolism after hip alloarthroplasty].

作者信息

Liedloff H, Schuh W, Heerdegen R

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1979;106(5-6):956-9.

PMID:94891
Abstract

The fibrinolytic therapy of massive frest pneumatic embolism represents an ensured progress today. Until now it was only possible to report on those cases where the patients had survived at least two hours from the beginning of the acute event. Two cases are reported here where the patients were successfully treated in spite of a standstill in the circulation. In a 60 years old female patient and 54 years old female hypertonic patient a successful reanimation could be performed in the early postoperative phase by applying a high dosage of awelysin. The progress indicated that the therapy has led to a lysis or partial lysis of embolus respectively and thus again to a perfusion of the lungs. At the same time the serious bleeding complications clearly indicate the limits of this aggressive form of intensive therapy.

摘要

目前,大规模新鲜空气栓塞的纤溶疗法已取得确凿进展。到目前为止,只能报告那些从急性事件开始起至少存活两小时的病例。本文报告了两例尽管循环停止但仍成功接受治疗的病例。在一名60岁女性患者和一名54岁女性高血压患者中,术后早期通过应用高剂量的阿魏溶素成功实现了复苏。进展表明,该疗法分别导致了栓子的溶解或部分溶解,从而再次实现了肺部的灌注。与此同时,严重的出血并发症清楚地表明了这种积极的强化治疗形式的局限性。

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