Rissanen P, Aro S, Sintonen H, Asikainen K, Slätis P, Paavolainen P
University of Kuopio.
Int J Technol Assess Health Care. 1997 Fall;13(4):575-88. doi: 10.1017/s0266462300010059.
The extensive benefits of the total hip (THA) and knee (TKA) replacements are well documented, but surprisingly little is known about their economics. We assessed costs, cost-effectiveness (C/E), and patient-related C/E variances in THA and TKA from data on 276 THA and 176 TKA patients. Patients with primary arthrosis, primary operation, and total joint replacement were recruited from seven hospitals between March 1991 and June 1992. Their use of health and other welfare services together with health-related quality of life (HRQoL) were measured before the surgery and at 6, 12, and 24 months postoperatively. HRQoL was assessed by the 15D, a 15-dimensional HRQoL instrument, and the Nottingham Health Profile. Costs were assessed from questionnaire responses, the Finnish Hospital Discharge Register, and Finnish Arthroplasty Register. Total hospital costs per patient were 45,000 FIM (US $10,500) for THA and 49,600 FIM (US $11,500) for TKA. Prosthesis costs comprised 21% of these costs in THA and 24% in TKA. On average, hip patients gained more in terms of HRQoL, and the operations were more cost-effective. The C/E ratio for younger (< or = 60 years) knee patients did not differ from those in all age groups of hip patients, whereas TKAs in those over 60 years had a worse C/E ratio compared with all other patient subgroups. It was concluded that allocation efficiency can be improved by considering not only the intervention but also patient characteristics such as age. Indeed, the C/E ratio varied more across age groups of knee patients than between average THA and TKA patients.
全髋关节置换术(THA)和全膝关节置换术(TKA)的广泛益处已有充分记录,但令人惊讶的是,人们对其经济学方面知之甚少。我们根据276例THA患者和176例TKA患者的数据,评估了THA和TKA的成本、成本效益(C/E)以及与患者相关的C/E差异。1991年3月至1992年6月期间,从七家医院招募了患有原发性关节炎、初次手术且进行全关节置换的患者。在手术前以及术后6个月、12个月和24个月,对他们使用健康和其他福利服务的情况以及与健康相关的生活质量(HRQoL)进行了测量。HRQoL通过15D(一种15维度的HRQoL工具)和诺丁汉健康量表进行评估。成本根据问卷调查回复、芬兰医院出院登记册和芬兰关节置换登记册进行评估。THA患者的人均总住院成本为45,000芬兰马克(10,500美元),TKA患者为49,600芬兰马克(11,500美元)。假体成本在THA中占这些成本的21%,在TKA中占24%。平均而言,髋关节患者在HRQoL方面获益更多,且手术的成本效益更高。年龄小于或等于60岁的膝关节患者的C/E比率与所有年龄组的髋关节患者无异,而60岁以上患者的TKA与所有其他患者亚组相比,C/E比率更差。研究得出结论,不仅要考虑干预措施,还要考虑年龄等患者特征,这样才能提高资源分配效率。事实上,膝关节患者不同年龄组之间的C/E比率差异比THA和TKA平均患者之间的差异更大。