Mitamura Y, Takeuchi S, Kasai H, Yamamoto S, Matsumura S, Kudou H
Department of Ophthalmology, Sakura Hospital, Toho University School of Medicine, Chiba-ken, Japan.
Nippon Ganka Gakkai Zasshi. 1998 Jan;102(1):59-63.
We performed a prospective study of corneal endothelial damage associated with pars plana vitrectomy in 51 eyes of 46 patients. The corneal endothelium was examined with a specular microscope preoperatively and three months postoperatively. The mean endothelial cell loss for 51 eyes was 11.54%. The 51 eyes were divided into three groups, and the mean cell loss was 25.85% in the pars plana lensectomy (including anterior capsule removal) combined group, 7.53% in the phacoemulsification combined group, and 1.91% in the phakic group. The corneal epithelium removal did not affected the cell loss. The cell loss for the phacoemulsification combined group did not differ significantly from that for the control group (6 eyes received only phacoemulsification). In the pars plana lensectomy combined group the cell loss was related significantly with gas tamponade duration. This study suggests that we must note the endothelial cell damage in vitrectomy-pars plana lensectomy combined with gas tamponade.
我们对46例患者的51只眼进行了一项关于玻璃体平坦部玻璃体切除术相关角膜内皮损伤的前瞻性研究。术前及术后三个月用角膜内皮显微镜检查角膜内皮。51只眼的平均内皮细胞损失率为11.54%。将51只眼分为三组，玻璃体平坦部晶状体切除术（包括切除前囊）联合组的平均细胞损失率为25.85%，超声乳化联合组为7.53%，有晶状体眼组为1.91%。角膜上皮切除不影响细胞损失。超声乳化联合组的细胞损失与对照组（6只眼仅接受超声乳化）相比无显著差异。在玻璃体平坦部晶状体切除术联合组中，细胞损失与气体填塞持续时间显著相关。本研究提示，在玻璃体切除术-玻璃体平坦部晶状体切除术联合气体填塞时，必须注意内皮细胞损伤。
