Bohm J, Bittigau K, Köhler F, Baumann G, Konertz W
Department of Cardiac Surgery, Charité University Hospital, Humboldt-University, Berlin, Germany.
Eur J Cardiothorac Surg. 1997 Dec;12(6):869-72. doi: 10.1016/s1010-7940(97)00270-4.
Since 1976 a number of similar transvenous atrial septal defect occlusion systems have been developed and applied to prevent surgical intervention with extracorporeal circulation and the complications involved. One of them is the so called atrial septal defect occlusion system (ASDOS-device; Dr Ing Osypka, Germany).
In our institution, eight ASDOS-devices were implanted in adults during the last year. In six individual cases, these devices were explanted because of thrombosis, residual shunts, deformations of the umbrella, disconnection of the system and atrial perforation with hemopericard. This occured 17-380 days after the implant. The surgical removal was uncomplicated in all cases.
Because the complication rate of the ASDOS-device was unacceptably high, surgical repair was preferred.
自1976年以来，已研发出多种类似的经静脉房间隔缺损封堵系统，并应用于避免体外循环手术干预及其相关并发症。其中一种就是所谓的房间隔缺损封堵系统（ASDOS装置；德国Ing Osypka博士）。
在我们机构，去年有8例成人植入了ASDOS装置。在6例患者中，由于血栓形成、残余分流、伞形装置变形、系统断开连接以及心包积血导致心房穿孔，这些装置在植入后17至380天被取出。所有病例的手术取出过程均无并发症。
由于ASDOS装置的并发症发生率高得令人无法接受，因此更倾向于手术修复。
