Vu-Duc T, Huynh C K, Savolainen H
IST-Institut universitaire romand de Santé au Travail, Lausanne.
Schweiz Med Wochenschr. 1997 Nov 29;127(48):2000-7.
Field surveys of diisocyanates at the workplaces in Switzerland and particularly in car repair shops, where HDI was the most used, showed that the monomer levels comply with the Swiss permissible exposure limit (PEL) in the great number of situations. Cases of medical surveillance associated with industrial hygiene measurements demonstrate that occupational asthma was also observed in situations where the monomer concentrations are low although high peaks of prepolymers are often recorded. From the statistical data on compensations, the annual incidence of occupational asthma over the period 1988 to 1992 remains around 54 cases with a mean cost of 21,000 sFr. per case per year. It is suggested that a PEL on the prepolymers should be introduced in the Swiss PEL list to enhance the efficiency of prevention policy.
在瑞士工作场所，尤其是汽车修理店（其中六亚甲基二异氰酸酯使用最为广泛）进行的二异氰酸酯实地调查表明，在大量情况下，单体水平符合瑞士职业接触限值（PEL）。与工业卫生测量相关的医学监测案例表明，尽管经常记录到预聚物的高峰值，但在单体浓度较低的情况下也观察到了职业性哮喘。根据赔偿统计数据，1988年至1992年期间职业性哮喘的年发病率约为54例，平均每例每年费用为21,000瑞士法郎。建议在瑞士职业接触限值清单中引入预聚物的职业接触限值，以提高预防政策的效率。
