Auger J, Perrotin D, Sonneville A
Service Réanimation Respiratoire 37044 CHU Tours.
Allerg Immunol (Paris). 2002 Oct;34(8):297-301.
Asthma from exposure to inhalation of isocyanates is an affection recognised under the title of work place diseases within table no 62 in the General Regulations and no 43 in the Agricultural Regulations. If workplace induced asthma is the most frequent of the workplace respiratory illnesses with a frequency of 2 to 15% of the asthmatic population, 1 patient in 2 will only be the object of a declaration and 1 in 3 the objective of a survey by the administrative authorities. The frequency of isocyanate asthma is on average 16.4% amongst workplace asthmas (19.6% in the industrial environment and 1.5% in an agricultural environment); if this prevalence is dose-dependent according to Baür, 30% of patients exposed to weak doses of isocyanate (0.3% ppb according to White) develop asthmatic disease whilst Bernstein estimates as 5 to 10% the frequency of asthmatic disease per 100,000 persons who are exposed to isocyanates.
因吸入异氰酸酯而引发的哮喘属于职业病，在《一般条例》表62及《农业条例》表43中被认定为职业病。如果说工作场所诱发的哮喘是工作场所呼吸道疾病中最常见的，在哮喘患者群体中的发病率为2%至15%，那么每2名患者中只有1名会申报，每3名患者中只有1名会成为行政当局调查的对象。异氰酸酯哮喘在工作场所哮喘中的平均发病率为16.4%（在工业环境中为19.6%，在农业环境中为1.5%）；根据鲍尔的说法，如果这种患病率与剂量有关，那么接触低剂量异氰酸酯（根据怀特的说法为0.3%百万分率）的患者中有30%会患上哮喘病，而伯恩斯坦估计，每10万名接触异氰酸酯的人中哮喘病的发病率为5%至10%。
