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[莫拉雷耶尔森氏菌WS 42/89菌株O-特异性多糖重复单元的结构]

[Structure of repeating unit of the O-specific polysaccharide from Yersinia mollaretii strain WS 42/89].

作者信息

Gorshkova R P, Isakov V V, Nazarenko E L, Shevchenko L S

出版信息

Bioorg Khim. 1997 Oct;23(10):823-5.

PMID:9490619
Abstract

The O-specific polysaccharide was isolated from Yersinia mollaretii strain WS 42/89 and characterized. Studies of the partial hydrolysis and methylation products and the 1H and 13C NMR spectroscopy data enabled the following structure to be proposed for the repeating unit of the polysaccharide: -->2)-beta-D-Galp-(1-->3)-alpha-D-6dGulp-(1--> The same structure was ascribed to the O-specific polysaccharide from Yersinia enterocolitica serovar O:6.31. The difference between these two O-antigens from various Yersinia species is in the absence of D-glycero-D-manno-heptose residues in the structure of the lipopolysaccharide from Y. mollaretii.

摘要

从莫氏耶尔森菌WS 42/89菌株中分离出O-特异性多糖并进行了表征。通过对部分水解产物、甲基化产物以及1H和13C核磁共振光谱数据的研究,提出了该多糖重复单元的如下结构:→2)-β-D-吡喃半乳糖-(1→3)-α-D-6-脱氧吡喃半乳糖-(1→ 小肠结肠炎耶尔森菌血清型O:6.31的O-特异性多糖也具有相同结构。这两种来自不同耶尔森菌属的O抗原之间的差异在于,莫氏耶尔森菌脂多糖结构中不存在D-甘油-D-甘露庚糖残基。

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