Nanni C A, Alster T S
Washington Institute of Dermatologic Laser Surgery, Washington, DC, USA.
Dermatol Surg. 1998 Feb;24(2):209-19. doi: 10.1111/j.1524-4725.1998.tb04139.x.
Continuous wave (CW) lasers, the first medical lasers to be used, continue to be effective, but are extremely operator dependent and can potentially result in significant risks, including scarring. In 1983, the theory of selective photothermolysis was introduced, which enabled physician-scientists to design lasers that were highly selective and safer to operate. These newer lasers are capable of affecting a specific target tissue without a high risk of scarring and pigmentary changes. They accomplish this task by producing a wavelength and pulse duration that is best absorbed by a specific target. However, not all modern lasers employ this theory and, therefore, may operate in either a CW, quasi-CW, pulsed, or Q-switched mode. CW lasers are least selective and tend to produce unwanted tissue damage and scarring through heat dissipation. Quasi-CW lasers attempt to limit unwanted thermal damage by producing a series of brief laser pulses or by the chopping of a CW beam; however, they still have a relatively high risk of causing nonspecific tissue damage and thermal injury. The pulsed and Q-switched systems adhere most closely to the principles of selective photothermolysis and result in the most selective destruction with the lowest risk of scarring and unwanted thermal diffusion. Of course, any laser system can potentially result in scarring and tissue damage; therefore, adequate operator education and skill are essential when utilizing medical lasers.
连续波(CW)激光是最早被使用的医用激光,至今仍有效果,但对操作人员的依赖性极强,且可能带来重大风险,包括形成疤痕。1983年,选择性光热作用理论被提出,这使得医学科学家能够设计出选择性高且操作更安全的激光。这些新型激光能够作用于特定目标组织,而产生疤痕和色素沉着变化的风险较低。它们通过产生特定目标最易吸收的波长和脉冲持续时间来完成这项任务。然而,并非所有现代激光都采用这一理论,因此可能以连续波、准连续波、脉冲或调Q模式运行。连续波激光选择性最差,往往会因热量消散而造成不必要的组织损伤和疤痕。准连续波激光试图通过产生一系列短暂的激光脉冲或切断连续波光束来限制不必要的热损伤;然而,它们仍有相对较高的风险导致非特异性组织损伤和热损伤。脉冲和调Q系统最严格地遵循选择性光热作用原理,造成的破坏最具选择性,产生疤痕和不必要的热扩散的风险最低。当然,任何激光系统都可能导致疤痕和组织损伤;因此,使用医用激光时,操作人员接受充分的培训并具备相应技能至关重要。