Cheng K, Goldman R J
Department of Rehabilitation Medicine, University of Pennsylvania, Philadelphia 19104, USA.
Bioelectromagnetics. 1998;19(2):68-74. doi: 10.1002/(sici)1521-186x(1998)19:2<68::aid-bem2>3.0.co;2-1.
In a dermal wound model, consisting of human skin fibroblasts in collagen matrix, continuous sinusoidal electrical current stimulation elicited a maximum increase of [3H]thymidine relative to control at 41 mV/m amplitude, 10 Hz. In this paper we elaborate cell cycle kinetics, using the same parameters. Labeling occurred over 4-h intervals beginning at 12 to 20 h after onset of electric exposure. The results suggest a significant increase in [3H]thymidine incorporation over an 8-h period extending from 16-24 hours after stimulus initiation.
