Gout-Lemerle M, Rodary C, Sarrazin D
Arch Fr Pediatr. 1976 Jun-Jul;33(6):537-53.
Non Hodgkin Lymphomas are in children nostly diffuse and non or poorly differentiated. The exact frontiers with ALL are difficult to assess. With old classical treatments, the chances of cure were limited to localized tumors (stage I). The present indications of combined intensive chemotherapies, of neuromeningeal prophylaxis, and radiotherpy are analyzed. Preliminary results in 51 children treated first in 1973-1974 are presented. The rate of complete remission is 82%. Actuarial survival rate is 57% at 30 months. The aim and the limitations of treatment protocol are discussed.
非霍奇金淋巴瘤在儿童中大多为弥漫性，且多为未分化或低分化。与急性淋巴细胞白血病的确切界限难以评估。采用旧的经典治疗方法时，治愈机会仅限于局限性肿瘤（I期）。本文分析了联合强化化疗、神经脑膜预防和放疗的当前适应证。介绍了1973 - 1974年首先治疗的51例儿童的初步结果。完全缓解率为82%。30个月时的精算生存率为57%。讨论了治疗方案的目的和局限性。
