LaRaja R D
Arch Surg. 1976 Sep;111(9):1028-31. doi: 10.1001/archsurg.1976.01360270100020.
Nonsyphilitic interstitial keratitis and deafness was first described as a distinct entity by Cogan in 1945. For years thereafter, it was believed to involve only the ocular and aural systems. It is gradually becoming apparent that the syndrome can also include other organ systems by affecting their blood supply. A patient with diagnosed Cogan syndrome subsequently developed mesenteric vascular insufficiency that was surgically corrected. This report lends more support to the belief that nonsyphilitic interstitial keratitis with deafness is only one manifestation of a more generalized vascular disease.
非梅毒性间质性角膜炎和耳聋于1945年被科根首次描述为一种独特的病症。此后数年,人们认为它仅累及眼和耳系统。逐渐明显的是,该综合征还可通过影响其他器官系统的血液供应而累及这些系统。一名被诊断为科根综合征的患者随后出现了肠系膜血管供血不足,并接受了手术矫正。本报告进一步支持了以下观点,即伴有耳聋的非梅毒性间质性角膜炎只是一种更广泛的血管疾病的一种表现。