Mafe M A
Public Health Division, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Acta Trop. 1997 Dec;68(3):277-84. doi: 10.1016/s0001-706x(97)00102-2.
Schistosomiasis is one of the major parasitic infections of man in the tropical and subtropical areas of the world. Diagnosis of the disease is usually based on microscopic detection of eggs in excreta which is both laborious and time consuming. In Nigeria, the Government's emphasis on the control of the disease dictates the need for a simple, fast, reliable and affordable diagnostic test for the identification of infected communities and detection of infected persons. Three indirect diagnostic tests for urinary schistosomiasis: interview technique, visual examination for macrohaematuria and the use of a chemical reagent strip were employed in screening 1056 individuals of the Kainji Lake area of Nigeria for urinary schistosomiasis, using haematuria as the disease indicator. The sensitivity of the three tests were determined using the filtration (egg counting) technique as the reference test. The sensitivity of the reagent strip test was 69.0% and 44 and 38% for the interview technique and visual examination respectively. The reagent strip test was particularly useful for screening children (5-19 years old). The implication of these findings are discussed.
血吸虫病是世界热带和亚热带地区人类主要的寄生虫感染疾病之一。该疾病的诊断通常基于对排泄物中虫卵的显微镜检测,这既费力又耗时。在尼日利亚,政府对该疾病控制的重视表明需要一种简单、快速、可靠且经济实惠的诊断测试,用于识别受感染社区和检测感染者。采用了三种用于尿路血吸虫病的间接诊断测试:访谈技术、肉眼血尿的目视检查以及使用化学试剂条,以血尿作为疾病指标,对尼日利亚卡因吉湖地区的1056人进行尿路血吸虫病筛查。以过滤(虫卵计数)技术作为参考测试来确定这三种测试的灵敏度。试剂条测试的灵敏度为69.0%,访谈技术和目视检查的灵敏度分别为44%和38%。试剂条测试对筛查儿童(5至19岁)特别有用。讨论了这些发现的意义。