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太空飞行后大鼠下丘脑 - 垂体神经分泌系统和肾脏功能变化的形态学表现

Morphological manifestations of functional changes in the hypothalamic-pituitary neurosecretory system and kidneys of rats after space flight.

作者信息

Savina E A, Pankova A S, Alekseyev E I, Podymov V K

出版信息

Aviat Space Environ Med. 1976 Aug;47(8):853-5.

PMID:949305
Abstract

Morphological examination of the hypothalamic-pituitary neurosecretory systen and kidneys of rats flown for 22 d and sacrificed 2 and 27 d postflight was carried out. By histological and histochemical methods, indications of increased activities of the hypothalamicpituitary neurosecretory system and the juxtaglomerular apparatus of kidneys were found. The changes were reversible and by the 27th postflight day returned to the normal. It is suggested that the changes in the above systems may be produced not only by flight effects but also by readaptation of animals to 1 g.

摘要

对飞行22天并在飞行后2天和27天处死的大鼠的下丘脑 - 垂体神经分泌系统和肾脏进行了形态学检查。通过组织学和组织化学方法,发现下丘脑 - 垂体神经分泌系统和肾脏球旁器的活性增加。这些变化是可逆的,在飞行后第27天恢复正常。有人认为,上述系统的变化可能不仅是由飞行效应引起的,也是动物重新适应1g重力的结果。

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