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本文引用的文献

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Conformations of polypeptides with ionized side chains of equal length.具有等长离子化侧链的多肽构象。
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1122-9. doi: 10.1073/pnas.60.4.1122.
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Application of laser Raman spectroscopy to the structural analysis of polypeptides in dilute aqueous solution.激光拉曼光谱在稀水溶液中多肽结构分析中的应用。
FEBS Lett. 1970 May 1;7(4):330-334. doi: 10.1016/0014-5793(70)80197-1.
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Conformations of poly-L-valine in solution.溶液中聚-L-缬氨酸的构象
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The helix-coil transition of poly-L-lysine in methanol-water solvent mixtures.聚-L-赖氨酸在甲醇-水混合溶剂中的螺旋-卷曲转变
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Conformational studies of poly-L-alanine in water.水中聚-L-丙氨酸的构象研究。
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Calorimetric measurement of enthalpy change in the isothermal helix--coil transition of poly-L-lysine in aqueous solution.水溶液中聚-L-赖氨酸等温螺旋-线圈转变过程中焓变的量热法测量。
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Raman scattering of some synthetic polypeptides: poly(gamma-benzyl L-glutamate), poly-L-leucine, poly-L-valine, and poly-L-serine.一些合成多肽的拉曼散射：聚（γ-苄基-L-谷氨酸）、聚-L-亮氨酸、聚-L-缬氨酸和聚-L-丝氨酸。
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Raman spectra of poly-L-lysines.
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9
Potentiometric titration of poly-L-lysine: the coil-to-beta transition.聚-L-赖氨酸的电位滴定：从卷曲态到β折叠态的转变
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Conformation of polypeptides and proteins.多肽和蛋白质的构象
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利用偏振拉曼技术研究聚-L-赖氨酸在甲醇水溶液中的构象

Study of poly-L-lysine conformations in aqueous methanol solution by using polarized Raman techniques.

作者信息

Shepherd I W

出版信息

Biochem J. 1976 Jun 1;155(3):543-8. doi: 10.1042/bj1550543.

DOI:10.1042/bj1550543
PMID:949317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1172876/
Abstract

Raman polarization measurements of the amide I band are reported in ionized poly-L-lysine dissolved in aqueous methanol. The observed changes with methanol concentration, attributed to changes in coil conformation and to the helix-coil transition, represent a novel method of measuring polymer conformation. Polarization measurements as a function of temperature yield values of the energy differences between rotational isomeric states in the coil. deltaH, of 8.8 +/- 0.7, 10.4 +/- 1.1 and 10.8 +/- 1.5 kJ/mol at methanol concentrations (v/v) of 85, 80 and 70% respectively. The stabilization energy of the helix is estimated at 9.3 kJ/mol.

摘要

报道了在溶解于甲醇水溶液中的离子化聚-L-赖氨酸中酰胺I带的拉曼偏振测量结果。观察到的随甲醇浓度的变化，归因于线圈构象的变化和螺旋-线圈转变，代表了一种测量聚合物构象的新方法。作为温度函数的偏振测量给出了线圈中旋转异构体状态之间能量差的值。在甲醇浓度（v/v）分别为85%、80%和70%时，ΔH分别为8.8±0.7、10.4±1.1和10.8±1.5 kJ/mol。螺旋的稳定能估计为9.3 kJ/mol。