关于红皮盐杆菌中缺乏脱氧核糖核酸暗修复的证据。
Evidence for the lack of deoxyribonucleic acid dark-repair in Halobacterium cutirubrum.
作者信息
Grey V L, Fitt P S
出版信息
Biochem J. 1976 Jun 15;156(3):569-75. doi: 10.1042/bj1560569.
Abstract
- Halobacterium cutirubrum does not perform dark-repair of DNA either after u.v. irradiation or during normal growth. 2. Cultures irradiated with u.v. are readily photoreactivated, but do not recover viability in the dark. 3. No increase in the rate of DNA synthesis is observed in the surviving cells after u.v. irradiation. 4. At early times during normal semiconservative replication, newly incorporated thymidine is found only in the hybrid DNA. 5. It is suggested that these bacteria may be useful in the study of DNA replication and photoreactivation.
摘要
- 深红嗜盐菌在紫外线照射后或正常生长期间都不进行DNA的暗修复。2. 经紫外线照射的培养物很容易发生光复活，但在黑暗中不能恢复活力。3. 紫外线照射后，存活细胞中未观察到DNA合成速率增加。4. 在正常半保留复制的早期，新掺入的胸腺嘧啶仅存在于杂种DNA中。5. 有人认为这些细菌可能在DNA复制和光复活的研究中有用。
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